Technologies in
Histology
We make histology into clear interpretable data. Gubra is a leading CRO specialized in histology services using AI-assisted quantification of disease markers and therapeutic endpoints. Our full-range histology service is fully integrated with our in vivo platform to ensure efficient, complete and high-quality evaluation of study endpoints.
Why Gubra?
- Expert histology solutions
- Clinical endpoints to ensure translatability
- Histopathology hallmark stainings
- High‐throughput multiplex stainings
- AI-assisted quantitative histology
- AI-enabled unbiased histopathological scoring
Consult with Allison Butt
Senior Scientist, Scientific Sales
Get more information on our high troughput histology services.
Complete and high-quality histology analysis can move your drug pipeline forward
High-quality histology is essential in preclinical drug development to understand its mode of action. We offer routine and advanced histology services, including core histology, immunohistochemistry, multiplex immunofluorescence and RNAScope®. We offer a fully digitalized process with machine learning and deep learning-based image analysis together with high throughput python-based image analysis pipelines.
Main Offerings
Multiplexed IHC &
ISH endpoints
AI-based
histopathological scoring
Quantitative
Histology
Applicable to
all organs
Whole slide imaging (WSI) and digitial pathology
clear interpretable data
Histology Solutions
Histology and histopathology
- Specialized histochemical stains for a range of morphological structures
- Paraffin embedding & frozen tissue processing and sectioning
- Histopathological evaluation
- AI-enabled unbiased histopathological scoring and image analysis
Immunohistochemistry and immunofluorescence
- Reproducible and automated techniques
- High troughput automated staining (Dako48®)
- Optimized methods for a broad array of markers
- Protocol optimization
- Paraffin & frozen tissue samples
- Single & multiplex stainingCompatible with light sheet processed samples
In situ hybridization (RNAscope®)
- Reproducible and automated techniques (LeicaBondRX®)
- Chromogen & fluorescent detection
Single and multiplex staining - Combined with IHC-RNAScope®
- Customized probes and protocols
- Paraffin & frozen tissue samples
Digital image analysis
- Machine learning and deep learning-based image analysis (Visiopharm®)
- High throughput python-based image analysis pipelines
- Readouts for both quantity and location in tissue
- Reproducible and fast readouts
Digital pathology
- High resolution scanning (Aperio GT450® )
- High throughput analysis of whole slides images
- AI-based histopathological scoring
- Global costumer access via cloud based image sharing
Custom Services
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Reach out to our histology experts to learn how we can provide histological solutions tailored to your specific research needs
Related pages
For further information
Contact us
Gubra
Hørsholm Kongevej 11B
2970 Hørsholm
Denmark
+45 3152 2650