Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. 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PublicationParaoxonase-2 agonist vutiglabridin promotes autophagy activation and mitochondrial function to alleviate non-alcoholic steatohepatitis PublicationIncreased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis PublicationAtlas of exercise-induced brain activation in mice PublicationShared and distinct renal transcriptome signatures in 3 standard mouse models of chronic kidney disease PublicationTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment PublicationProtection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R PublicationDietary intervention reverses molecular markers of hepatocellular senescence in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PublicationTAAR1 Agonists Improve Glycemic Control, Reduce Body Weight and Modulate Neurocircuits Governing Energy Balance and Feeding PublicationEvaluation of long acting GLP1R/GCGR agonist in a DIO and biopsy-confirmed mouse model of NASH suggest a beneficial role of GLP-1/glucagon agonism in NASH patients PublicationSemaglutide reduces tumor burden in the GAN diet‑induced obese and biopsy‑confirmed mouse model of NASH‑HCC with advanced fibrosis PublicationWhole-brain activation signatures of weight-lowering drugs PublicationQuantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson’s disease PublicationIdentification of GDF15 peptide fragments inhibiting GFRAL receptor signaling PublicationUncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging PublicationFaecal microbiota transplantation affects liver DNA methylation in non-alcoholic fatty liver disease: a multi-omics approach PublicationRationale and design of a prospective, clinical study of kidney biopsies in people with type 2 diabetes and severely increased albuminuria (the PRIMETIME 2 study) PublicationGLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity PublicationHepatocyte mARC1 promotes fatty liver disease PublicationA3907, a systemic ASBT inhibitor, improves cholestasis in mice by multi-organ activity and shows translational relevance to humans PublicationHepatoprotective effects of the long-acting FGF21 analogue PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PublicationFASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models PublicationGIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650