Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. 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PosterClinical translatability of the GAN diet-induced obese and biopsy-confirmed mouse model of MASH WebinarUsing whole brain imaging for development of obesity drugs PosterPreclinical efficacy and clinical translatability of elafibranor in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PosterMetabolic, biochemical and histological effects of elafibranor in a CDAA-HFD induced non-obese rat model of advanced NASH with progressive fibrosis PosterWhole brain distributional changes of lipidated exendin-4 peptides PublicationElafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis PublicationValidity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH PublicationImpact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice PublicationGlobal transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss PublicationInvestigating intestinal glucagon after Roux-en-Y gastric bypass surgery PublicationRhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones PublicationCombined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH PublicationPancreatic β-cell rest replenishes insulin secretory capacity and attenuates diabetes in an extreme model of obese type 2 diabetes PublicationDisease progression and pharmacological intervention in a nutrient-deficient rat model of nonalcoholic steatohepatitis PublicationNovel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice PublicationMetabolic and hepatic effects of liraglutide, obeticholic acid and elafbranor in diet-induced obese mouse models of biopsy-confrmed nonalcoholic steatohepatitis PublicationApplication of the physical disector principle for quantification of dopaminergic neuronal loss in a rat 6-hydroxydopamine nigral lesion model of Parkinson’s disease PublicationGUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice PublicationIn-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes PublicationEnteroendocrine K and L cells in healthy and type 2 diabetic individuals PublicationA hydrogel-microsphere drug delivery system that supports once-monthly administration of a GLP-1 receptor agonist PublicationEarly depletion of CA1 neurons and late neurodegeneration in a mouse tauopathy model Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650