Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. 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steatohepatitis PosterCapillary, venous, and arterial vasculature 3D light sheet imaging and AI analysis in intact mouse organs PosterTransferrin receptor binding BBB-shuttle facilitates brain delivery of a therapeutic Aβ-antibody: A mouse whole-brain 3D light sheet imaging study PosterWhole-brain 3D imaging of Aβ plaque architecture following treatment with a BBB shuttle-enhanced Aducanumab biosimilar in a mouse model of AD PosterClinical translatability of the GAN diet-induced obese and biopsy-confirmed mouse model of MASH WebinarWhole organ staining and 3D light sheet imaging for pharmacological research PublicationWhole-brain activation signatures of weight-lowering drugs PosterWhole-brain activation signatures of weight-lowering drugs WebinarUsing whole brain imaging for development of obesity drugs PosterPreclinical efficacy and clinical translatability of obeticholic acid in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH WebinarWhole brain imaging using light sheet microscopy PosterQuantitative whole-brain 3D imaging of congophilic parenchymal and vascular amyloid plaque architecture in a transgenic mouse model of Alzheimer’s disease 3D imaging videoPlaques in an adult mouse brain PublicationDual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative PublicationWhole-brain 3D imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases PublicationResolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis PosterObeticholic acid improves histological, biochemical and gene expression profiles in Gubra AMLN mice with diet-induced and biopsy-confirmed NASH PublicationCombined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH PublicationDisease progression and pharmacological intervention in a nutrient-deficient rat model of nonalcoholic steatohepatitis PublicationINT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis PublicationMetabolic and hepatic effects of liraglutide, obeticholic acid and elafbranor in diet-induced obese mouse models of biopsy-confrmed nonalcoholic steatohepatitis PublicationGUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice PublicationEarly depletion of CA1 neurons and late neurodegeneration in a mouse tauopathy model Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650