Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. Filtered (25) Filters Reset all × Alk5 inhibitor × Alpha-synuclein × CB1 receptor × GAN ob/ob-MASH mouse × Gene expression × Neurobehavior × Taspoglutide × Search × Resource type Data presentation (0) Poster (11) Publication (12) 3D imaging video (0) Webinar (2) Category × Disease model (223) Cardiovascular disease (11) AngII mouse (2) DIO-ApoE-KO mouse (1) DIO-LDLR-KO mouse (4) DIO-PCK9-AAV mouse (1) Isoprenaline-induced cardiomyopathy (1) Cholangiopathy (1) Bile duct ligation (BDL) mouse (1) Mdr2-KO mouse (1) CNS disease (39) Alzheimer's disease models (9) CNS activation (12) Drug distribution (6) Gene expression (1) Gene therapy (1) Parkinson's disease models (6) Diabetes (33) db/db mouse (17) Non-obese diabetic (NOD) mouse (4) ZDF rat (10) Inflammatory bowel disease (3) Acute DSS-IBD mouse (0) Chronic DSS-IBD mouse (3) Idiopathic pulmonary fibrosis (7) BLEO-IPF mouse (4) Chronic BLEO-IPF mouse (2) HFD-BLEO-IPF mouse (0) Kidney disease (33) Acute kidney injury (4) Bilateral ischemia 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progression and ALK5i therapeutic efficacy in a chronic DSS-induced mouse model of IBD with intestinal fibrosis PosterReproducible lung protective effects of a TGFβR1/ALK5 inhibitor in the bleomycin-induced and spirometry-confirmed mouse model of IPF PosterHistological disease progression and ALK5i therapeutic efficacy in a chronic DSS-induced mouse model of IBD with intestinal fibrosis PosterProphylactic and therapeutic effects of the dual FXR/TGR5 agonist INT-767 in the GAN diet-induced ob/ob mouse model of advanced MASH with progressive fibrosis PosterReproducibility and therapeutic effects of ALK5i on pulmonary function and fibrosis in a bleomycin-induced and spirometry-confirmed mouse model of IPF PosterWhole-brain 3D mapping and quantification of pathological α-Synuclein aggregate spreading and toxicity in a mouse model of early-stage Parkinson’s disease PosterDose-dependent nephroprotective effects of an ALK5 inhibitor in the unilateral ureteral obstruction (UUO) mouse model of kidney fibrosis WebinarWhole organ staining and 3D light sheet imaging for pharmacological research PublicationWhole-brain activation signatures of weight-lowering drugs PosterWhole-brain activation signatures of weight-lowering drugs WebinarUsing whole brain imaging for development of obesity drugs PosterNephroprotective effects of an ALK5 inhibitor in the unilateral ureteral obstruction (UUO) mouse model of kidney fibrosis PosterMetabolic, biochemical, histological, and transcriptomic effects of semaglutide in the GAN diet-induced and biopsy-confirmed ob/ob mouse model of NASH PosterA3907, a novel inhibitor of bile acid transport in the intestine and the kidney, improves markers of metabolic and hepatic pathology and reduces NAFLD activity score and fibrosis stage in a diet-induced and biopsy-confirmed mouse model of nonalcoholic steatohepatitis PublicationTowards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source PublicationApplication of the physical disector principle for quantification of dopaminergic neuronal loss in a rat 6-hydroxydopamine nigral lesion model of Parkinson’s disease PublicationGUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice PublicationCharacterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson’s disease PublicationLong-term treatment with liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has no effect on β-amyloid plaque load in two transgenic APP/PS1 mouse models of Alzheimer’s disease PublicationThe GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy PublicationThe anti-diabetic effects of GLP-1-gastrin dual agonist ZP3022 in ZDF rats PublicationThe GLP-1 receptor agonist liraglutide improves memory function and increases hippocampal CA1 neuronal numbers in a senescence-accelerated mouse model of Alzheimer’s disease PublicationThe effect of leptin receptor deficiency and fasting on cannabinoid receptor 1 mRNA expression in the rat hypothalamus, brainstem and nodose ganglion Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650